123 Street, NYC, US 0123456789 info@example.com

上海千花网,爱上海,上海419论坛 - Powered by Nanci Alec!

hcjmnsgv

first_imgAuthorities on Monday made heavy deployment of police and Central Reserve Police Force to maintain law and order as the separatists called protest shutdown affected life across the Kashmir Valley.“Etiquette deployments have been made to maintain the law and order situation on Monday,” a senior police official said.Eight protesters were killed when the security forces opened fire during the voting process in the Srinagar-Budgam parliamentary by-poll on Sunday.Of these, seven were killed in Budgam and one died in Ganderbal district.Mobs attacked the polling stations, damaging the EVMs and ransacking the polling stations, at nearly 100 places in Budgam.Separatists have called a two-day shutdown and protest against Sunday’s civilian killings.Markets, public transports, education institutions and other businesses remained closed here and other places in the valley.The Kashmir University has postponed all the examinations that were scheduled for Monday and Tuesday.Chief Electoral Officer (CEO) Shant Manu on Sunday said that re-poll would be held at 50 to 100 polling stations where violence had resulted in the disruption of polling process.Around seven per cent votes were polled during Sunday’s by—poll which marked the lowest voter turnout in the last 27 years.The CEO has said that the next phase of the by—poll would be held on schedule on April 12 in south Kashmir’s Anantnag parliamentary constituency.Meanwhile, to check the spread of rumours by anti—social elements authorities have decided to suspend the internet facility in the entire valley till April 12.last_img read more

wvehpdnk

first_img, An army jawan posted along the Line of Control (LoC) in Poonch district of Jammu and Kashmir was killed in an accidental discharge from his service weapon.This is second such death of an army jawan in less than 24 hours in the district.The jawan deputed on a forward post along the LoC in Mendhar sector of Poonch district received bullet wounds due to accidental fire and later died on Tuesday, a senior Army officer said He has been identified as Ravinder Singh.On Monday night, a jawan deputed on a forward post along the LoC in Mendhar sector of Poonch district received bullet wounds due to accidental fire from his weapon and later died, Defence spokesman Lt Col Manish Mehta had said. He was identified as Sepoy Manmohan Budhani (23).The Defence spokesman had denied reports in a section of the media that the soldier died in Pakistani firing.last_img read more

rsgqllsv

first_imgIn a shot in the arm for the on-going agitation for a separate State of Gorkhaland, president of the Jan Andolan Party (JAP) and prominent leader of the Darjeeling hills, Harkha Bahadur Chettri on Friday voiced his support for the movement. Mr Chettri said also he was willing to join the forum of political parties calling for a separate State including the Gorkha Janmukti Morcha (GJM).High Court directive In a related development, the Calcutta High Court on Thursday directed the West Bengal government to restore peace and normalcy in the Darjeeling hills.The directions, passed by a division bench of acting Chief Justice Nishita Mhatre and Justice T Chakraborty, reiterated earlier orders of the Supreme Court and the Calcutta High Court that shutdowns or general strikes are illegal. The court also asked GJM representatives to be present during the next hearing on June 23.Arson reportedA cash counter of the Rimbick Hydel power plant and a primary health centre in Darjeeling were set on fire by miscreants as incidents of violence and arson were reported at various places in the Darjeeling hills. The Tarakhola forest bungalow at Kalingpong, a primary school, and a gram panchayat office at Merik were also destroyed by arsonists. The GJM denied its involvement in the violence but the police claimed to have arrested several GJM leaders in connection with the violence.Rival returnsMr Harkha Bahadur Chettri, a former GJM MLA from Kalimpong, had floated the JAP in January 2016. He also contested the 2016 Assembly polls with the support of ruling Trinamool Congress.“We were always in support of Gorkhaland. To join the forum of political parties I have given some conditions to the GJM. We are willing to join the other political parties provided our demands are met,” Mr Chettri told The Hindu.He said with “emotions running high on Gorkhaland”, the JAP has launched its programme. Earlier, the Gorkha National Liberation Front (GNLF), one an arch rival, joined the GJM and participated in a meeting on June 13 with five other parties.Court seeks report In another development, the Calcutta High Court directed the principal secretary of the State Home Department to submit an interim report within two weeks on after assessing the damage caused to the public property during the shut down since June 9.The directive came during the hearing of a PIL petition, with the Court citing its 2013 order terming shutdownsjudgement where it has termed bandhs illegal. The court asked the West Bengal government to take necessary steps to prevent such incidents. The court also asked GJM representatives to be present during the next hearing on June 23. Violence and Arson Meanwhile incidents of violence and arson were reported at various places in the Darjeeling hills over the past 24 hours after the GJM called for a complete shutdown on Thursday after a raid on its president Bimal Gurung’s residence in Patleybas. A cash counter of the Rimbick Hydel power plant and a primary health centre in Darjeeling were set on fire by miscreants. The Tarakhola forest bungalow at Kalingpong, a primary school, and a gram panchayat office at Merik were also destroyed by arsonists. The GJM denied its involvement in the violence but the police claimed to have arrested several GJM leaders in connection with the violence.The Mamata Banerjee government has send seven more IPS officers to control the situation in the Darjeeling hills. At this moment more than a dozen of IPS officers along with three columns of area and paramilitary forces are deployed in Darjeeling. Earlier in the day Army and CRPF personnel held an area domination exercise in Patleybas which has turned violent on Thursday. A huge contingent was also deployed before GJM headquarters at Singamari.On the second day of the indefinite shutdown, life in Darjeeling town came to a complete standstill with shops, commercial establishments, hotels and educational institutions remaining closed. The streets of the country one of the most sought after holiday destination bore a deserted look with hardly any tourists and only a few locals coming out of their homes.last_img read more

fjnahbfq

first_imgAmid a face-off between Indian and Chinese troops along the India-China border, the Kailash-Mansarovar Yatra through the Nathu La pass in Sikkim has been cancelled.However, pilgrims travelling through the Lipulekh pass in Uttarakhand will continue as scheduled, a government official said.The annual Kailash Mansarovar Yatra was flagged off earlier this month by External Affairs Minister Sushma Swaraj. However, China had declined permission for the first group of 50 pilgrims to proceed to Mount Kailash through the Nathu La pass. The pilgrims had to return to Gangtok after they were denied permission. Eight batches, each comprising around 50 pilgrims, were scheduled to take the Nathu La route to Mansarovar in Tibet. The route through the Nathu La pass that opened two years ago shortens the entire distance, making the pilgrimage less arduous. The Lipulekh route involves a treacherous trek of about 200 km, while the Nathu La route calls for trekking for only 35 km.(With PTI inputs)last_img read more

rsgqllsv

first_imgTwo Union Ministers, Jitendra Singh and Hansraj Gangaram Ahir, who praised the Kashmir civil society for condemning the attack on Amarnath pilgrims, said on Wednesday that “India is in the last phase of militancy.”“We are here on behalf of Prime Minister Narendra Modi to express our solidarity. The common youth of Kashmir is keen to be part of the development journey led by the Prime Minister,” said Dr. Jitendra Singh, Minister of State, Prime Minister’s Office. He said the unanimous condemnation “clearly indicates that there is no place for such acts in the Valley.” “I hail and appreciate the widespread condemnation. Earlier there used to be a selective condemnation,” Dr. Singh said. Refusing to name the group behind the attack, which left seven pilgrims dead, Dr. Singh said, “No one should jump to any conclusion. Let’s wait for definite inputs from the security agencies.” The Ministers met Governor N.N. Vohra and Chief Minister Mehbooba Mufti, besides security agencies, and discussed the security situation. “The collective response showed no one can kill Kashmiriyat. After many years everyone in Kashmir is on the same page on something. We all believe this [the attack] is not what Kashmir stands for,” Ms. Mufti reportedly told the Ministers. ‘Nationalistic rhetoric’Reacting to Dr. Singh’s remarks, separatist leaders Syed Ali Geelani, Mirwaiz Umar Farooq and Yasin Malik, said in a joint statement: “Resorting to nationalistic rhetoric, denial of ground realities and degrading the resistance leadership will not help in changing the grave situation in Kashmir for the better.” A number of tour and travel bodies condemned the attack, with tourist hotspot Pahalgam witnessing a shutdown over the incident.Srinagar youth in militant ranksMeanwhile, three Hizbul Mujahideen militants were killed in an encounter at Budgam. Two of them belonged to Srinagar, which was a militancy-free zone for 12 years. The Valley witnessed clashes, stone-throwing and curfew-like restrictions during their funeral. The three were trapped in a house during a cordon operation in the Redbugh area. “They were engaged in a gunfight till morning. The house was blasted with improvised explosive devices. All the three bodies were recovered from the debris,” said a police official. One self-loading rifle (SLR) and a pistol were recovered from the encounter site. The police are verifying if the SLR was a snatchedservice rifle.The police identified the slain militants as Aaqib Gul, a resident of Srinagar’s Goripora area, Sajid Ahmad Gilkar of Srinagar’s Malaratta, and Javaid Ahmad Sheikh from Budgam’s Beerwah.Ground realityIt was in 2005 that two militants from Srinagar, Ibrahim Dar and Ishfaq Ahmad Rather, were killed in an encounter on the city outskirts. Since then, Srinagar was declared a militancy-free zone with no local armed militant. In the past one year, the police figures suggest that 11 youth from Srinagar have turned to militancy.A resident of the old city, Gilkar, who was a known protester and booked under the Public Safety Act (PSA) on several occasions, had joined militancy just 10 days ago.Curfew-like restrictions were imposed in the city to keep protesters at the bay. Major clashes broke out when the militant’s body reached Nowahatta. Locals alleged that security forces used pellet shotguns on the mourners. Scores of protesters were injured. Earlier in the day, several areas witnessed spontaneous shutdown and stone throwing.Four rounds of funeral prayers were held for slain Sheikh in Budgam. Protesters were seen marching on the city roads at Hyderpora and performed the funeral of Gul on the roadside. Demonstrators’ attempt to go to Hurriyat chairman Syed Ali Geelani’s residence was disallowed by the security forces.Youth were seen unfurling the banners of Hizb commander Burhan Wani and split faction head Zakir Mussa during these funerals. Clashes broke out on the road connecting the airport with the city as youth raised anti-India slogans.last_img read more

jfybhhoh

first_imgResponding to reports questioning its claim, the Uttar Pradesh government on Tuesday clarified that the mysterious substance found last week under a chair in the State Assembly was indeed a deadly explosive, pentaerythritol tetranitrate (PETN).The State Home Ministry, a department directly under the control of Chief Minister Yogi Adityanath, issued the clarification after some reports suggested that the substance recovered from the Assembly was not an explosive.Some media outlets on Monday had reported, relying on sources, that tests conducted at the Forensic Science Laboratory (FSL) in Agra had indicated that the substance was not PETN.Also Read Explosive found in UP Assembly; Yogi Adityanath seeks NIA probe  The State government has stood by its stand and said that the “preliminary test conducted using explosive detection kit” tested positive for PETN at the Lucknow FSL.The laboratory in the state capital in its report on July 14 had found the substance as “water insoluble” and that “different reagents confirm the presence of a nitrate.”Sample not sent to AgraIt also said that samples of the substance were not sent to Agra for testing in the first place.“It is to clarify that no sample of the substance has been sent to FSL Agra as they do not have the machines/wherewithal to conduct the requisite tests,” the UP Home Ministry said.This appeared to contradict the information on the police website which states that “cases related to explosives are examined at Agra FSL only.”Final report by July 20The government also said that two confirmatory tests are still being conducted at FSL Lucknow. Their report is likely to be out by Thursday.A major controversy was created on July 14 when Mr. Adityanath informed the U.P. Assembly that a mysterious packet discovered under a bench in the House two days earlier was identified as PETN by forensic tests.Mr. Adityanath, while alleging a “terrorist conspiracy”, promptly called for a probe by the National Investigation Agency (NIA).With the U.P. Anti-Terror Squad (ATS) probing the case, security has been beefed up at the Assembly.As a security measure, the government has cancelled the vehicle passes of more than 700 former legislators and plans to conduct police verification of all staff working in the Assembly.The ATS has already recorded the statements of 15 officials and staff members who were on duty in the House on the day the packet was found. The ATS questioned one assistant Marshall, 4 engineers, 2 security personnel, one AC operator, and seven grade-4 staff members.It has also gathered all the footage from the 23 CCTV devices installed in the Assembly.last_img read more

tzxidfjj

first_imgHeavy showers in the last 72 hours have resulted in a surge in the water stocks of the four main dams which constitute the city’s potable water lifeline. The showers have helped make up the rainfall deficit which bedevilled the city last month and relieving fears of a possible water shortage.After Nashik and Solapur, Pune recorded a healthy surplus (nearly 50 %) for the season. The storage of the Khadalwasla dam – the city’s main supplier – rose beyond the 50% mark for the first time this season with its stock climbing up to 1.15 TMC, while Panshet and Varasgaon recording a healthy rise in water stocks, reaching 5 TMCft and 5.11 TMCft respectively.Authorities said the continuous rainfall was a positive sign as this year the Temghar dam, whose maximum storage capacity is 3.15 TMCft, is out of action owing to repair work. The collective storage of the four dams exceeded the halfway-mark, standing at a robust 53.70% with incessant rain in the catchment areas bolstering the water level in the past week. Meanwhile, the Koyna dam has filled up to 60 TMC of its 105 TMC, said officials. The city has, so far, received 285mm rainfall this season, 53 mm excess than the normal mark. The meteorological department has forecasted heavy rains for western and central Maharashtra in the coming days. Incessant bouts of rain in Kolhapur district for the past four days saw a number of villages being cut off with the water levels of the Panchganga River rising precariously, exceeding its ‘danger mark’. The downpour has all but paralyzed traffic in the city since the beginning of the week with the district recording more than 30 mm rainfall in the last 12 hours.According to the district administration’s disaster management cell, heavy rain was recorded in the catchment areas of Shahuwadi, Radhanagari and Gaganbawda tehsils of the district. Officials said that the Ghatprabha and Kode dams were completely filled, while the rest were more than 60% full.last_img read more

skxowwxh

first_imgNagaland Director General of Police (DGP) Rupin Sharma has initiated a move to shut moneylenders out of the department.In an order on Wednesday, Mr. Sharma set up a seven-member committee for exploring the possibility of providing short-term loans to police personnel from the Nagaland Police Risk Insurance Scheme (NPRIS).This was primarily to dissuade constables, officers of lower ranks and other staff from taking loans from private moneylenders.“From interactions with police personnel across all units of Nagaland police, we came to know that taking loans from private moneylenders at exorbitant interest rates of up to 25% has become a habit for many,” Mr. Sharma said.It was also learnt that unit commanders and drawing and disbursing offers had sometimes been deducting the principal amount and interest money in cash before demitting the salaries to the bank accounts of the police personnel, his order said.“The degree of financial literacy was not up to the mark and this has created not only financial problems but also fostered other ills in the management of the force,” the order said. The Nagaland police department had about 26,000 employees. Each employee contributed a specific amount – currently ₹150 – every month to NPRIS. The monthly deposit in the scheme from regular contributors works out to an average ₹24,500.“The short-term loan mechanism was being worked out since NPRIS has a system of payouts on retirement or death. This is just the beginning of the process with detailed recommendations expected soon,” Mr. Sharma told The Hindu.The committee headed by ADG (law and order) Renchamo P Kikon has been asked to submit report by April 25.last_img read more

osrwtvum

first_imgFour children were injured when a mobile phone battery exploded at Lunguri village in Ganjam district of Odisha on Monday. According to police sources, the children were playing with a discarded mobile phone battery when the blast occurred. The injured children were between 10 and 12 years. Luckily none of them received lethal injury in the blast, the sources said. One of the children had found a discarded phone battery and they were trying to connect it to an LED bulb when it exploded. Another incidentIn a similar incident, a 13-year-old student of Class VIII was injured on Monday at Kalimatu village of Nupada district when the battery of a mobile phone exploded. The incident happened when the boy was charging the phone. His right eye was completely damaged.On March 17, a girl named Uma Oram (18) of Kheriakani village of Jharsuguda district died when the battery of her cell phone exploded while she was talking. The mobile phone was connected to the charger at the time of the incident.last_img read more

zpsdmffj

first_imgA doctor-turned-model-turned-actor and her cook were taken into preventive custody after a scuffle broke out between the two, the police said on Friday. However, hundreds of domestic workers held a protest under the banner of Gharelu Kamgar Union accusing the police of high-handedness and sought the Deputy Commissioner’s intervention.According to Maya Das, who works as a cook at the house of Tina Chatwal, 38, a former Miss Asia Pacific, her employer was angry when she did not find the meal cooked to her liking and began to beat her up. Ms. Chatwal allegedly grabbed her by hair, kicked her in the stomach, and slapped her several times. She was later taken to Paras Hospital.SHO, Sector 53, Arvind Dahiya said both the help and her employer claimed to have been roughed up by each other. “We had a complaint from the help and a counter-complaint from her employer. Both had got their medical examination done and procured the Medico-Legal Certificate. So both were taken into preventive custody and produced before the Deputy Commissioner of Police, Headquarters,” said Mr. Dahiya. The two were later let off. But Maya John of GKU alleged in a letter to Deputy Commissioner Vinay Pratap Singh that the police were favouring the employer. She pointed out in her letter that the injuries to the help were visible and undeniable and prior to taking the help into custody “the police did not collect the CCTV footage of the accused’s apartment” complex which shows the employer brutally beating up the domestic worker”.last_img read more

uiihphxo

first_img The phase 1 involves building a 77 m-tall and a 2 km-wide dam, the Dhaudhan dam, and a 230 km canal to transfer extra water from the Ken river for irrigating 3.64 lakh hectares in the Bundelkhand region of Uttar Pradesh and Madhya Pradesh.Originally, this phase envisaged irrigating 6,35,661 ha (hectares) annually (3,69,881 ha in M.P. and 2,65,780 ha in U.P.). In addition, the project was to provide 49 million cubic metres (MCM) of water for en route drinking water supply.No longer validWhile there’s a 2005 agreement between the two States on how water would be shared, Madhya Pradesh said last year that these assumptions were no longer valid and the only way to meet increased water requirements would be to include certain local water management projects — the Kotha barrage, Lower Orr and Bina complex that were envisaged in the second phase of the project — in the first phase.In theory, this could mean a completely fresh environmental appraisal. The Central Water Commission is yet to officially take a call, though government sources say the Centre is agreeable to the change. However, new demands by Madhya Pradesh for more water during the Rabi season are yet to be negotiated. Disagreements over water-sharing and difficulty in acquiring non-forest land impede the ₹18,000-crore Ken Betwa river interlink project.The scheme, which involves deforesting a portion of the Panna Tiger Reserve in Madhya Pradesh, was accorded clearance by the National Wildlife Board on the condition that the land lost would be made good by acquiring contiguous, revenue land. This is to ensure that wildlife corridors in the region aren’t hit. “The M.P. government has said that they are facing major difficulties over this,” said a senior person in the Water Ministry involved with the project.Unlikely this yearAnother hurdle is a dispute over how Uttar Pradesh and Madhya Pradesh — the two beneficiaries — will share water in the Rabi season.These “major” issues made it quite unlikely that the project will get under way this year. A person familiar with the deliberations told The Hindu, “New points of differences between the two States are constantly being raked up…there are still many things to be ironed out before the project can be sent for the [Union] Cabinet’s approval.”Conceived as a two-part project, this is the country’s first river interlinking project. It is perceived as a model plan for similar interstate river transfer missions.last_img read more

osrwtvum

first_imgAccused Sunil Kumar arrested in connection with the rape and murder of a three-year-old girl earlier this month had abducted and killed seven more girls — aged between 3 to 8 years — after raping them in separate cases in Gurugram, Delhi and Madhya Pradesh over the past two years, the police said on Tuesday.Of the seven victims, two are from Gurugram, three from Delhi and one each from Gwalior and Jhansi, said DCP (Crime) Sumit Kuhar.From religious placesThe 20-year-old Sunil would abduct minor girls from near bhandaras (community feasts) at religious places. Then he would rape and later kill them, the police said. He would also abduct minor girls from slums when their parents would be away for work.Mr. Kuhar said the accused would brutalise his victims — break their limbs — before killing them.Sunil had confessed to the murders during interrogation and the facts were being verified from the police stations concerned, the officer said.Besides the rape and murder of the three-year-old, abducted from a slum cluster in Sector 66 on November 11, Sunil had kidnapped a girl from outside a temple on Sohna Road in November 2016 and another girl at Civil Lines in January last. Both the girls were raped and murdered.In the present case, the victim was subjected to brutality during rape causing severe injuries to her private parts. She was hit with a heavy object and died due to head injuries. Mr. Kuhar said the police have questioned around 2,000 vagabonds sleeping on the roads during an extensive search operation for the accused. “We had information that he preferred to eat at community feasts at religious places and slept on the roads. We conducted three community feasts on November 13, 22 and 24 laying a trap for him,” said Mr. Kuhar.Sunil ate at a gurudwara and spent the night at Nehru Park after the commission of crime on November 11. He then reached Delhi and took a train to Uttar Pradesh on the next day after spending the night under Nizamuddin bridge.The senior police officer said on the earlier two occasions, the police had no clue but this time around he was seen luring the victim. He was also captured on a CCTV camera at a group housing society along with his victim and his relatives also provided his picture.The accused is from UP’s Mahoba district. He was nabbed from at UP’s Magapur village on Monday. Sunil was produced before the court in the afternoon and remanded in eight days police custody, the police said.last_img read more

oykplife

first_imgIt takes a lot to deter a male from wanting sex. A new study has found that male mice keep trying to copulate even when they are in pain, whereas females engage in less sex. But when given drugs that target pleasure centers in the human brain, the females again became interested. The findings could shed light on the nature of libido across various animal species.To assess how pain influences sexual desire, researchers first identified pairs of mice that wanted to have sex. “What we found early on was not all mice will mate with each other,” says clinical psychologist Melissa Farmer, who led the study while earning her Ph.D. at McGill University in Montreal, Canada. The team set up the rodents on a series of “dates,” during which a male and female were paired together for 30 minutes. Couples that copulated for most of the session were deemed compatible and moved into a cage with separate rooms. A small doorway allowed a female mouse to freely cross over from her chamber, but the male—which is larger—could not.The scientists then induced pain in males or females by applying a small dose of inflammatory compounds to the cheek, tail, foot, or genitals. The sensation would primarily be soreness, like a bad sunburn, says Farmer, who now works at Northwestern University’s Feinberg School of Medicine in Chicago, Illinois.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Female mice that were in pain, whether genital or nongenital, spent 50% less time with their male partners, implying a decrease in sexual motivation. Even when they did visit their paramours, females wouldn’t allow males to mount them with the same frequency, the team reports online today in The Journal of Neuroscience.The researchers then set up the reverse scenario in which males dictated the encounters. They placed both mice in an “open-field” cage with no barriers. Males desired just as much sex even if they were in pain, and the researchers observed no significant difference in mounting attempts or other sexual behaviors.Pain-relieving drugs increased females’ willingness to mate, and two sex-drive enhancers—apomorphine and melanotan II—did the same. Both drugs tweak neural circuits tied to pleasure and arousal.Women exercise more caution when selecting a mate, which many psychologists attribute to cultural expectations, such as when female modesty is pushed by some religions. In other words, social norms might impose female repression of sexual desire. In contrast, Farmer and her colleagues conclude, somewhat controversially, that women might simply be more biologically prone to sexual repression in certain contexts.Jill Becker, a behavioral neuroscientist at the University of Michigan, Ann Arbor, supports the idea. “It’s valid given the amount of female investment [in reproduction] and the way that these systems must have evolved to ensure reproductive success.”Yet other researchers hesitate to build such a major bridge between mice and man. “Claiming an evolutionary basis to sexual behavior based on one study trivializes the rich complexity of human behavior,” says Barry Komisaruk, a behavioral neuroscientist at Rutgers University, Newark, in New Jersey. “It implies inevitability to a woman’s behavior—that she has no voluntary control. That’s too much to extrapolate from one mouse study.”last_img read more

blmnsvvg

first_imgAs red blood cells zip through vessels, they deliver oxygen to nearly every nook and cranny of your body. But oxygen isn’t all they can tote around. By engineering red blood cells to have “sticky” proteins on their surface, a team of researchers has given the cells the ability to carry anything from drugs to treat immune disorders or cancer to radioactive molecules used in imaging of blood vessels.“This is really a great idea, and a very novel approach,” says biochemist Vladimir Muzykantov of the University of Pennsylvania, who was not involved in the new work.Red blood cells account for a quarter of all human cells in the body and survive for an average of 4 months. Their ubiquity and long life makes them an ideal vehicle to carry therapeutics throughout the body, says immunologist Hidde Ploegh of the Massachusetts Institute of Technology in Cambridge. Previously, researchers have loaded red blood cells with drugs by pushing the molecules through the cell’s membrane into its interior, but the process weakens the cell, and the molecules are released only when the cell reaches its final destination.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Ploegh and his colleagues instead wanted to attach molecules to the outside of red blood cells. Because red blood cells don’t have nuclei—and therefore lack genetic material that can be tweaked to make new proteins—the researchers turned to erythroblasts, precursors to red blood cells that still contain DNA. The scientists added to erythroblasts altered versions of genes that are known to encode proteins found on the surface of red blood cells. The introduced gene sequences, though, had modifications so that the erythroblasts produced surface proteins with an extra marker that’s recognized by a protein called sortase.Those engineered proteins remained as the erythroblasts matured into red blood cells. When the researchers added sortase to the matured cell mixtures, the protein snipped off the ends of any proteins the researchers had genetically modified, leaving “sticky” trailer hitches for cargo. Any molecule with a corresponding sortase tag would then bind to the surface protein on the red blood cell. To show that the hitch would work, Ploegh’s team attached the vitamin biotin to red blood cells and infused them into mice. The biotin-toting cells survived for at least 28 days in circulation and did not harm the mice, they report online today in the Proceedings of the National Academy of Sciences.Ploegh envisions the technique being used to create a new type of personalized therapy in the future—your own cells could be isolated, used to create stem cells that differentiate into erythroblasts, genetically modified to carry a molecule, and reinjected into your body. Any molecule that needs to be spread through the circulatory system could be the cargo. By the time the cells have matured back into red blood cells, they will have lost their DNA, eliminating the risk of ongoing mutations or the spread of genetic materials. “The payloads you can install are limitless,” Ploegh says. “But a lot of the applications are still, for now, hypothetical.”Muzykantov, who has developed other approaches for using red blood cells as molecular vehicles, says the significance of the new method “exceeds just drug delivery.” It could be used to track red blood cells to diagnose blood diseases, spread imaging agents throughout the body to visualize atherosclerotic plaques or blocked arteries, or neutralize the immune system before transplants by blocking antibodies that enter the bloodstream.“But there are lots of questions to address in animal models,” he adds. “I would love to see a demonstration that a real drug binds to a red blood cell using this approach and is still effective.”last_img read more

vxxyohxe

first_imgWhat is the meaning of water clouds detected just 7 light-years from Earth? What can walking fish tell us about how the first animals adapted to land? And why are humans so nice to each other? Science’s Online News Editor David Grimm chats about these stories and more with Science’s Sarah Crespi.last_img

cmzgzdbq

first_imgGut surgery is often the only option for life-threatening obesity and diabetes, but what if doctors could cut the pounds without using a knife? Scientists have engineered an antiobesity drug that rivals the dramatic benefits seen with surgery, dropping excess body weight by a third. Though the work was done only in rodents, the drug is the first to influence three obesity-related hormones in the gut at once.Bariatric surgery, including gastric bypass, typically involves limiting food intake by removing part of the stomach or intestines. Yet it does more than shrink the size of patient’s stomach or intestines. It also changes the release of multiple gut-related hormones, explains clinical endocrinologist Stephen O’Rahilly of the University of Cambridge in the United Kingdom, who wasn’t involved with the study. That’s important, because years of eating a diet high in fat and sugar can throw a person’s metabolism into disarray. Cells undergo genetic reprogramming that negatively impacts how they process sugar and store fat, locking in obesity. This pattern makes it harder and harder to lose weight, even if a person changes their diet and begins exercising.Bariatric surgery interrupts that cycle by stimulating the production of several hormones that reduce blood sugar, burn fat, and curb appetite. (It may also change the composition of the gut’s microbes.) Three of these hormones are called glucagon-like peptide-1 (GLP-1), gastric inhibitory peptide (GIP), and glucagon. Cells in your gut release GLP-1 and GIP after a meal to keep your body’s blood sugar levels in a normal range. GLP-1 also curbs appetite, signaling to your brain that you are full. In type 2 diabetes, the body stops responding to GLP-1 and GIP, which contributes to hyperglycemia, or too much blood sugar. Hyperglycemia causes the devastating hallmarks of diabetes, such as kidney injury, cardiovascular disease, and nerve damage.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Glucagon, in contrast, causes blood sugar levels to rise by telling the liver to convert fat into sugar. As hyperglycemia progresses in diabetes, the body shuts the hormone off in a presumed attempt to restore sugar balance, but that also stymies fat burning. In normal people and bariatric surgery patients, glucagon lowers fat and can trigger weight loss.Existing medications can individually boost the levels of each of these hormones, but the drugs have a limited effect on obesity and diabetes. For instance, GLP-1 drugs only shave off an average of about 2.7 kilograms in human trials and also have unfortunate side effects like severe nausea and vomiting. These challenges have convinced many researchers that “the way forward with obesity drug therapy is hitting more than one gut hormone at once,” O’Rahilly says.So that’s what endocrinologist Matthias Tschöp, research director of the Helmholtz Diabetes Center in Munich, Germany, and colleagues set out to do. They engineered a protein that takes structural pieces of GLP-1, GIP, and glucagon and merges them into a single molecule. To create the hybrid, the team started with an engineered protein that combined GLP-1 and glucagon, then spent years making small changes to add GIP components. Each time a tweak was made, the researchers would test the hybrid hormone in cells or mice to see if it still stimulated each hormone pathway. By the end, they had a drug packed with the power to turn on glucagon, GLP-1 and GIP signals, but not other hormone systems—an unprecedented feat for obesity drug design.When given to obese and diabetic rodents, the drug triggered metabolic changes—glucose lowering, fat burning, and weight loss—to the same degree that bariatric surgery had in previous studies. The compound caused the rodents’ body weight to drop by a third, on average, over 3 weeks and cut their blood glucose in half. It also reduced fat mass by a third, while keeping healthy lean mass intact, Tschöp and his colleagues report online today in Nature Medicine.“Think of this as an injectable elixir that could reverse obesity and type 2 diabetes by cheating a body into believing that it just received a gastric bypass,”  Tschöp says. That means a commercial drug based on this research could potentially confer the benefits of bariatric surgery without the risks of a physical operation.The project required some remarkably clever chemistry and is one of the more thorough evaluations of a drug for obesity and diabetes, O’Rahilly says, though he points out that true test will come in humans. ”In the end, you don’t throw a party until you have a drug that works in people.”last_img read more

vzdqgrsq

first_imgResearchers have increased the size of mouse brains by giving the rodents a piece of human DNA that controls gene activity. The work provides some of the strongest genetic evidence yet for how the human intellect surpassed those of all other apes.”[The DNA] could easily be a huge component in how the human brain expanded,” says Mary Ann Raghanti, a biological anthropologist at Kent State University in Ohio, who was not involved with the work. “It opens up a whole world of possibilities about brain evolution.”For centuries, biologists have wondered what made humans human. Once the human and chimp genomes were deciphered about a decade ago, they realized they could now begin to pinpoint the molecular underpinnings of our big brain, bipedalism, varied diet, and other traits that have made our species so successful. By 2008, almost two dozen computerized comparisons of human and ape genomes had come up with hundreds of pieces of DNA that might be important. But rarely have researchers taken the next steps to try to prove that a piece of DNA really made a difference in human evolution. “You could imagine [their roles], but they were just sort of ‘just so’ stories,” says Greg Wray, an evolutionary biologist at Duke University in Durham, North Carolina.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Wray is particularly interested in DNA segments called enhancers, which control the activity of genes nearby. He and Duke graduate student Lomax Boyd scanned the genomic databases and combed the scientific literature for enhancers that were different between humans and chimps and that were near genes that play a role in the brain. Out of more than 100 candidates, they and Duke developmental neurobiologist Debra Silver tested a half-dozen. They first inserted each enhancer into embryonic mice to learn whether it really did turn genes on. Then for HARE5, the most active enhancer in an area of the brain called the cortex, they made minigenes containing either the chimp or human version of the enhancer linked to a “reporter” gene that caused the developing mouse embryo to turn blue wherever the enhancer turned the gene on. Embryos’ developing brains turned blue sooner and over a broader expanse if they carried the human version of the enhancer, Silver, Wray, and their colleagues report online today in Current Biology.The researchers determined that HARE5 likely controls a gene called Frizzled 8, which is part of a molecular pathway important in brain development. Their further studies showed that the human version of the enhancer causes cells that are destined to become nerve cells to divide more frequently, thereby providing a larger of pool of cells that become part of the cortex. As a result, the embryos carrying human HARE5 have brains that are 12% larger than the brains of mice carrying the chimp version of the enhancer. Silver and Wray plan to test these mice to see if the bigger brains made them any smarter.”They have found a smoking gun in the human genome that connects a regulatory element with a proposed pathway for increasing brain size,” says Todd Preuss, a neuroanatomist at the Yerkes National Primate Research Center in Atlanta, who was not involved with the work.But he; geneticist Evan Eichler of the University of Washington, Seattle; and others point out that there’s more to be done. Several researchers worry that more extensive studies are needed to nail down that the HARE5 effects are not by chance. They’d like to see Silver and her colleagues replace the mouse HARE5 with the human and chimp HARE5—a feat the Duke group has yet to succeed in doing.Even so, Eichler is pleased with just how much the Duke team has learned so far. And, Wray says, given the growing ability of researchers to study enhancers and other DNA in mice, “my guess is there are probably other stories like this in the works.”last_img read more

rsgqllsv

first_imgWhat brought Indians to the United States, and what made Indian immigrants, as a whole, so successful once here? Related Itemslast_img

jvtbbmru

first_imgThe Hard Rock Hotel & Casino in Punta Cana, Dominican Republic, has a “Hindu” pizza on its menu containing “chicken tikka masala with yogurt, cilantro and mint,” and this has upset some Hindus.In a statement, Hindu statesman Rajan Zed, President of the Universal Society of Hinduism, termed it as a trivialization of the oldest and third largest religion of the world with about 1.1 billion adherents and a rich philosophical thought.Read it at NewsIndiaTimes Related Itemslast_img read more

oykplife

first_imgIn my cultural world, two major events defined the beginning of the year 2009 — the Obama inaugural and the movie Slumdog Millionaire.Both events are meaningfully connected in the popular culture. There is a synergy between the improbable victory of Obama in the presidential elections and the Hollywood/Bollywood rags to riches caper that went on to win the Oscar for the best picture of the year. Barack Obama, a half-Kenyan American, from Hawaii via Indonesia and Chicago has taken on the mantle of the first African American and the first global president of the United StatesBoth stories are about outsiders who come from the fringes of society yet manage to prevail against all the odds. Obama, a half-Kenyan American, from Hawaii via Indonesia and Chicago, has taken on the mantle of the first African American and the first global president of the United States.The key protagonist in Slumdog Millionaire is a young man, named Jamal, an orphan Muslim minority from one of the poorest slums in Mumbai, India. He not only manages to get on the popular game show, Who wants to be a Millionaire, but to the dismay of the game show host and the local police authorities, is able to correctly answer all the questions to take home the coveted prize.Both narratives are also about the power of globalization. Obama’s win represents the triumph of the American brand of multiculturalism at home and abroad, won on the backs of the hard-fought victories of the civil rights movement and the emerging post-racial world.Slumdog Millionaire represents the flush of new capital pouring into big metro areas like Mumbai, extolling the virtues of American greed and the free market economy, over the two thousand years old Hindu work-ethic encapsulated in the Bhagavad Gita, which professes that one should perform one’s duties (dharma) as self-less action (karma) and not to be motivated by the fruits of one’s labor or profits.To the disappointment of many educated and diaspora Indians, who are part and parcel of the emerging “incredible India,” it is clear that old stereotypes are hard to change. In the movie, India continues to be depicted as “a vast public latrine,” as V. S. Naipaul said in An Area of Darkness almost 50 years earlier, but at least now it’s part of the back office of American corporations and other multinational firms.Finally, both Obama and Slumdog represent a wave of populism that surfaces in hard economic times. Notwithstanding the hard-boiled film-making of Danny Boyle, the English/Irish director well-known for making gritty films about the downtrodden, the story of the orphan slum dwellers touches American hearts, because the global economy is in an abysmal dump. Thus, a brutal yet beautiful film makes us appreciate how blessed we really are as Americans and how good we really have it. The key protagonist in Slumdog Millionaire, named Jamal, an orphan Muslim minority from one of the poorest slums in Mumbai, not only manages to get on the popular game show Who wants to be a Millionaire, but to the dismay of the gameshow  host and the local police authorities takes home the coveted prize.Observing the populist elation at the Obama victory, Frank Rich wrote in the New York Times, “We’ll soon remember that the country is in a deep ditch, and that we turned to the black guy not only because we hoped he would lift us up, but because he looked like the strongest leader to dig us out.”However, populism can easily turn into rage against its chosen heroes. The actors in Slumdog Millionaire learned this when they returned home from the Oscars to angry mobs of slum dwellers who were upset at being depicted as a colony of sub-human species. Recently, the Obama dawg millionaires have not been spared the populist outrage either at their perceived lack of connection with the American people over the banking crisis and the dolling out of whopping AIG bonuses.And therein may be the perils for Obama as well. Related Itemslast_img read more