Gut surgery is often the only option for life-threatening obesity and diabetes, but what if doctors could cut the pounds without using a knife? Scientists have engineered an antiobesity drug that rivals the dramatic benefits seen with surgery, dropping excess body weight by a third. Though the work was done only in rodents, the drug is the first to influence three obesity-related hormones in the gut at once.Bariatric surgery, including gastric bypass, typically involves limiting food intake by removing part of the stomach or intestines. Yet it does more than shrink the size of patient’s stomach or intestines. It also changes the release of multiple gut-related hormones, explains clinical endocrinologist Stephen O’Rahilly of the University of Cambridge in the United Kingdom, who wasn’t involved with the study. That’s important, because years of eating a diet high in fat and sugar can throw a person’s metabolism into disarray. Cells undergo genetic reprogramming that negatively impacts how they process sugar and store fat, locking in obesity. This pattern makes it harder and harder to lose weight, even if a person changes their diet and begins exercising.Bariatric surgery interrupts that cycle by stimulating the production of several hormones that reduce blood sugar, burn fat, and curb appetite. (It may also change the composition of the gut’s microbes.) Three of these hormones are called glucagon-like peptide-1 (GLP-1), gastric inhibitory peptide (GIP), and glucagon. Cells in your gut release GLP-1 and GIP after a meal to keep your body’s blood sugar levels in a normal range. GLP-1 also curbs appetite, signaling to your brain that you are full. In type 2 diabetes, the body stops responding to GLP-1 and GIP, which contributes to hyperglycemia, or too much blood sugar. Hyperglycemia causes the devastating hallmarks of diabetes, such as kidney injury, cardiovascular disease, and nerve damage.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Glucagon, in contrast, causes blood sugar levels to rise by telling the liver to convert fat into sugar. As hyperglycemia progresses in diabetes, the body shuts the hormone off in a presumed attempt to restore sugar balance, but that also stymies fat burning. In normal people and bariatric surgery patients, glucagon lowers fat and can trigger weight loss.Existing medications can individually boost the levels of each of these hormones, but the drugs have a limited effect on obesity and diabetes. For instance, GLP-1 drugs only shave off an average of about 2.7 kilograms in human trials and also have unfortunate side effects like severe nausea and vomiting. These challenges have convinced many researchers that “the way forward with obesity drug therapy is hitting more than one gut hormone at once,” O’Rahilly says.So that’s what endocrinologist Matthias Tschöp, research director of the Helmholtz Diabetes Center in Munich, Germany, and colleagues set out to do. They engineered a protein that takes structural pieces of GLP-1, GIP, and glucagon and merges them into a single molecule. To create the hybrid, the team started with an engineered protein that combined GLP-1 and glucagon, then spent years making small changes to add GIP components. Each time a tweak was made, the researchers would test the hybrid hormone in cells or mice to see if it still stimulated each hormone pathway. By the end, they had a drug packed with the power to turn on glucagon, GLP-1 and GIP signals, but not other hormone systems—an unprecedented feat for obesity drug design.When given to obese and diabetic rodents, the drug triggered metabolic changes—glucose lowering, fat burning, and weight loss—to the same degree that bariatric surgery had in previous studies. The compound caused the rodents’ body weight to drop by a third, on average, over 3 weeks and cut their blood glucose in half. It also reduced fat mass by a third, while keeping healthy lean mass intact, Tschöp and his colleagues report online today in Nature Medicine.“Think of this as an injectable elixir that could reverse obesity and type 2 diabetes by cheating a body into believing that it just received a gastric bypass,” Tschöp says. That means a commercial drug based on this research could potentially confer the benefits of bariatric surgery without the risks of a physical operation.The project required some remarkably clever chemistry and is one of the more thorough evaluations of a drug for obesity and diabetes, O’Rahilly says, though he points out that true test will come in humans. ”In the end, you don’t throw a party until you have a drug that works in people.”
November 30, 2019
LATEST STORIES Frontrow holds fun run to raise funds for young cancer patients Brace for potentially devastating typhoon approaching PH – NDRRMC E.T. returns to earth, reunites with grown-up Elliott in new ad Kammuri turning to super typhoon less likely but possible — Pagasa Alex Gordon hits MLB’s record-setting 5,694th HR of season MOST READ Trending Articles PLAY LIST 00:50Trending Articles00:50Trending Articles00:50Trending Articles01:37Protesters burn down Iran consulate in Najaf01:47Panelo casts doubts on Robredo’s drug war ‘discoveries’01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games Fire hits houses in Mandaluyong City LOOK: Loisa Andalio, Ronnie Alonte unwind in Amanpulo for 3rd anniversary It has been a rather unexpectedly good start to the season for Barcelona, which began the league amid turmoil after seeing Neymar leave for Paris Saint-Germain and losing the Spanish Super Cup match to Real Madrid.It is the best start to the league for Messi, who in 2011-12 had scored eight goals after five matches.He is the league’s leading scorer, with four goals more than Simone Zaza of Valencia, who had a hat trick in a 5-0 rout of Malaga earlier Tuesday.“He is one of the smartest players I’ve ever seen on a field,” Barcelona coach Ernesto Valverde said of Messi. “You don’t really know how, but he is always in good position. He is extraordinary.”It was the fourth time Messi has scored four goals or more with Barcelona.ADVERTISEMENT FC Barcelona’s Lionel Messi scores a penalty during the Spanish La Liga soccer match between FC Barcelona and Eibar at the Camp Nou stadium in Barcelona, Spain, Tuesday, Sept. 19, 2017. (AP Photo/Manu Fernandez)MADRID — Lionel Messi added to his impressive start to the season by scoring four goals and helping Barcelona rout Eibar 6-1 to extend its perfect record in the Spanish league on Tuesday.Messi converted a penalty in the first half and scored three more goals in the second to give Barcelona its fifth straight victory in the league.ADVERTISEMENT Don’t miss out on the latest news and information. Nonong Araneta re-elected as PFF president BSP sees higher prices in November, but expects stronger peso, low rice costs to put up fight Brazil midfielder Paulinho and Denis Suarez also scored for the Catalan club, while Sergi Enrich netted Eibar’s goal.Barcelona was without Ousmane Dembele, who injured his left thigh at the weekend and is expected to be sidelined for up to four months. The young France forward, Barcelona’s top signing during the transfer window, traveled to Finland to undergo surgery on a ruptured tendon. He made only three appearances after arriving to replace Neymar.Valverde left Luis Suarez on the bench and started with Gerard Deulofeu, Denis Suarez and Messi as a false “9″ in the attack. Paulinho, the Brazil midfielder who came off the bench to score the winner against Getafe on Saturday, also made it to the starting lineup.“Today we have been able to rest certain players and give playing time to others who needed to play and it turned out well,” Valverde said.___LOSING AGAINValencia won 5-0 with a hat trick by Simone Zaza to hand Malaga its fifth straight loss to start the season.Zaza scored his three goals eight minutes apart early in the second half to give Valencia its first victory after three straight draws and move the club into third place.Forward Santi Mina and Rodrigo also scored for the hosts at Mestalla Stadium. Read Next The Argentina playmaker took his tally to 12 goals in eight matches this season, including nine in the five league games.Messi had already scored a hat trick in Barcelona’s 5-0 rout of Espanyol in the Catalan derby two rounds ago.FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSSEA Games: Philippines picks up 1st win in men’s water poloSPORTSMalditas save PH from shutoutThe result gave Barcelona a five-point lead over Sevilla, which hosts Las Palmas on Wednesday. Real Sociedad, six points back, is at Levante on Thursday.Defending champion Real Madrid, seven points behind Barcelona, hosts Real Betis on Wednesday. View comments
November 19, 2019
Juventus’s outstanding display to knock Barcelona out of the Champions League will have the rest of Europe running scared of the Old Lady, defender Leonardo Bonucci said on Wednesday.Juve served Barca a two-year-old dish of revenge for defeat in the 2015 Champions League final with a comprehensive 3-0 beating last week in Turin and followed it up by holding the Catalans to a goalless draw at the Nou Camp to reach the European Cup semi-finals for a 12th time. (Barcelona paid for mistakes in first leg: Luis Enrique)”It’s not about who we don’t want to face because none of the other teams want to face us. Juventus provoke fear in everyone else and now our objective is to reach the final,” Bonucci told reporters after helping shut out Barca’s usually prolific attack for a second game running.”We showed great unity and solidarity. We have belief in ourselves, because scoring three goals against Barcelona and keeping a clean sheet at the Nou Camp shows we are a great team. Now there are another two steps to go.”This side deserves praise for how we approache every game, whether we’re playing Barcelona or Pescara,” added the Italy defender, whose side have conceded two goals in 10 games in the Champions League this campaign.”This is another step for our growth and now every opponent will worry about facing Juventus.”Juve have monopolised their domestic league since 2011-12 and are on course for a sixth consecutive Serie A crown this season although they have a comparatively poor record in continental competitions, winning Europe’s biggest prize twice, in 1985 and 1996.advertisementCaptain Gianluigi Buffon hopes the comprehensive win over five-times European champions Barcelona is a sign his side are ready to take the next step.”We started growing a few years ago and we need to continue on it,” added the goalkeeper.”It can’t just stop or plateau after this victory. It’s down to us now, our destiny is in our own hands. When it comes down to who wins the trophy, fate has a hand in that too.”
October 28, 2019
About the authorPaul VegasShare the loveHave your say Chelsea captain Azpilicueta: Youngsters will grow with Champions Leagueby Paul Vegas21 hours agoSend to a friendShare the loveChelsea captain Cesar Azpilicueta praised their youngsters after they beat Champions League opponents Ajax in Amsterdam.Youngsters Tammy Abraham, Mason Mount, Fikayo Tomori and Callum Hudson-Odoi all started in the imposing Johan Cruyff ArenA. Michy Batshuayi jumped from the bench to grab the winner.Azpilicueta said, “We knew we had to work hard as a team and we did. Everybody worked very hard, the 11 starters and the subs.”Everyone is pushing everyone. It’s important to be a team off the pitch because that gives everyone extra energy.”To have the young lads playing in the Champions League in the capacity they are doing, with the quality they are showing, is massive.”For them, the progression, to play at the level they are playing, is amazing.”
October 22, 2019
The Amherst Access Nova Scotia Centre at the Superstore Mall and the Land Registry Office on Havelock Street will be closed on Friday, Nov. 23. Both offices will re-open Monday, Nov. 26, in the new Access Nova Scotia Office at 144 Robert Angus Dr. next to Robin’s Donuts. “The new, shared space lets us serve the people of Amherst and surrounding areas more efficiently,” said Service Nova Scotia and Municipal Relations Minister John MacDonell. “It will also allow us to evolve to keep pace with our client’s changing needs.” For inquiries, call 1-800-670-4357, or access available online services at www.gov.ns.ca/snsmr/access/online-services.asp.
October 20, 2019
Akasa Singh became a household name soon after the release of her first Bollywood song ‘Kheech Meri Photo’ from the 2016 Bollywood movie Sanam Teri Kasam. And since then, there has been no looking back for her. The 25-year-old singer started her career with Mika Singh where she was the only girl in a band of 10 male members. Thereafter, she was seen as a contestant in ‘India’s Raw Star’ which further added to her fame.However, the ‘Kheech Meri Photo’ singer feels that she has not achieved all this stardom and success overnight. “I started performing when I was 17, and it took 7-8 years of constant struggle and hard work to reach where I am today.” Also Read – ‘Will be acting till I die’Unveiling the reality behind a celebrity’s life, Akasa further adds, “It appears to be lavish and smooth from a distance. It seems like I have achieved a lot in my life, I have become a celebrity. But to be honest, the struggle behind it, that constant effort cannot be seen or told.” Performing with other singers in the initial phase of her career, Singh is now an independent artist. And her mantra for success is – “This is what I want, this is what I will do” and this is what keeps her going. Also Read – ‘Always looking for that one great love’Akasa says that apart from the opportunities she is getting in Bollywood, she is even focussing on her independent music as she believes that it helps her expand her horizons. Keeping up the popularity and expectations of her fans, Akasa released a duet with Ricky Martin titled ‘Vene Pe Ca’ in the year 2017. The singer also has a mashup of Ed Sheeran’s ‘Shape of you’ and Badsha’s ‘Mercy’ to her credit along with a cover version of ‘Zara Zara’. And finally what made her a sensation was debut pop single ‘Thug Ranjha’, which was uploaded on Youtube in May 2018. The music video crossed 27mn + views within a month and became the most watched Indian video worldwide on YouTube. YouTube helped the singer become a social media sensation, but only in the later stage career. She believes it is a good medium which provides opportunities and helps the hidden talent come out to the front. “I myself feel that YouTube helped me a lot, but only in the later stage. I uploaded a video of my song and got appreciated for it. But I think many people get it a lot easier, and they don’t know how to value it afterward.” Akasa is just 25 and has become a sensation among youth, but she likes to believe that she has not reached the ‘stardom’ point yet. “I think there is a long way to go, higher space to attain.” Sharing her experience of working with Vishal and Shekhar in the song ‘Aithey aa’, Akasa tells Millennium Post that it was a fun experience and they are coolest music directors on the face of the earth. It is her second Bollywood number, but she has generally been associated with peppy numbers in the past too. Does that bother her? “One song gets popular, so the composers and audience label you in that category. They create an image of yours and you are given work in that genre. This is the reason I have been always called for the peppy numbers. Though, as an artist, I do not want to be stereotyped. I am here to explore, I want my voice to be heard in a different kind of music.”
October 14, 2019
John Murray APTN National NewsAfter schedule changes and delays, the National Inquiry into Missing and Murdered Indigenous Women and Girls (MMIWG) is set to begin hearings Tuesday in a community along the so-called Highway of Tears in B.C.Smithers sits halfway between Prince George and Prince Rupert along Hwy. 16, named the Highway of Tears because of the number of Indigenous women who have vanished or have been found dead along it.One of those women is Tamara Chipman, 22, who disappeared in 2005.Her aunt, Gladys Radek, has walked the highway every year for the last seven years.The final day of Gladys’ walk is Monday which takes her into Smithers.Chief Commissioner Buller, and commissioners Robinson and Audette will be joining Gladys for the final segment of her walk.The second round of hearings were originally scheduled in Thunder Bay, Ont., but those hearings were moved to December.Hearings in Saskatoon, and Rankin Inlet, Nunavut have also been postponed.Delays, rescheduling, and high-level resignations have dogged the inquiry since it was announced in August 2016.Recently the Assembly of Manitoba Chiefs, Southern Chiefs’ Organization, Assembly of First Nations Manitoba, and Manitoba Keewatinowi Okimakanak voiced concerns and called for a Manitoba subcommission led by a Manitoban.While speaking to a Senate committee lead Buller cited restraints imposed by government policy and procedure contributed to delays, and she plans on asking for more time.Indigenous-Crown Relations Minister Carolyn Bennett told APTN National News that the government will consider an extension when the plan is formally requested.An interim report is due in November and a final report expected December 2018.Contact John here: email@example.com
October 12, 2019
Rabat – Qatar Airways will hold a cabin crew recruitment event in on May 13 at La Tour Hassan Palace hotel in Rabat.The international airline is looking to expand their cabin crew team by recruiting new candidates enthusiastic about flying. Eligible candidates must be at least 21 years old, fluent in spoken and written English, and hold at least a high school education. In addition to interpersonal skills and the ability to work with a multinational team, applicants must also be in good health and physical condition. ”Known for our 5 star hospitality, we look for future Cabin Crew who can be part of our World Class Global Brand,” said the international airline in a press release.
October 12, 2019
Rabat – Morocco finished at the top of the overall rankings of the first African Beach Games organized from June 14 to 23 at Sal Island in Cape Verde. Morocco won 16 medals, including 9 gold, 3 silver, and 4 bronze.Moroccan athletes competed in open water swimming, kiteboarding, karate, freestyle football, beach volleyball, beach tennis, beach handball, and beach soccer. Morocco won the gold medals in beach tennis with the men’s doubles, Youssef Ghazouani and Anas Bouaouda clinching the win. In the women’s doubles, Morocco’s Camilia Benabdeljalil and Sarah Benabdeljalil were the victors, and the mixed doubles saw Anas Bouaouda and Camilia Benabdeljali go for gold.Read also: Bid for Morocco’s SAMIR Refinery amid Fresh, Unsettled ControversiesOthmane Djedidi also won a gold in freestyle football. El Hanni Mohammed (men’s individual kata) and Sanae Agalmam (women’s individual kata) won gold medals as well for karate. In the women’s team kata, 1st place went to En-nesyry Aya, Bertali Lamiae, Agalmam Sanae.In open water swimming (5km), the gold medal went to Ben Rahou Mathy, and in beach volleyball, the gold went to the Moroccan women’s team.Second place went to Algeria with 16 medals (5 gold, 6 silver and 5 bronze), while Tunisia took third place (3 gold, 3 silver and 1 bronze). Cape Verde, the game’s host country, took 4th place (3 gold, 2 silver and 5 bronze).The first African Beach Games saw the participation of 886 athletes, including 416 female athletes, in 11 sports competitions included in the official program of the Games.
October 8, 2019
MONTREAL — The founder and former chief executive of Amaya Inc. has sold about two-thirds of his remaining shares in the Montreal-based owner of PokerStars, for a total of $267.7 million.David Baazov received an average of $22.31 per share for the 12 million Amaya shares that he sold on Wednesday and Thursday.Prior to this week’s sales, Baazov owned about 17.6 million Amaya shares — or 12 per cent of its common stock.That drops to 3.8 per cent of Amaya’s shares following this week’s transactions, which were disclosed late Thursday.PokerStars owner Amaya eyes acquisitions after long, difficult period of paying down debtRobust customer registrations and lower costs help Amaya beat analyst expectations in fourth quarterIt’s Baazov’s second large divestiture this month. He announced March 7 that had sold seven million Amaya shares at an average price of $19 per share, totalling $133 million.Baazov had proposed early last year to buy Amaya and take it private, but walked away from the bid in December after running into legal problems.He has pleaded not guilty to securities-related charges that were announced following an investigation into allegations of illicit trading by several close associates over a five-year period.
October 3, 2019
by Crystal Laderas Posted Feb 29, 2016 2:09 pm MDT Alberta Transportation will tackle Uber issues AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email Transportation Minister Brian Mason announced a plan to develop a reasonable framework for ride-for-hire companies such as Uber, which vowed to stop service in the province by Tuesday if the government didn’t support its proposed insurance framework.“Our plan ensures customers who use ride-for-hire services are safe, that the people who transport have the necessary skills and knowledge, and that there is insurance in place in the event of an accident,” states Mason in a news release.The province says by July 1, it will have an interim insurance product ready to provide coverage for Uber drivers and passengers. It says drivers will need at least a Class 4 licence, which is mandatory in most provinces for taxis and other commercial transportation services. The government also says all drivers will need to undergo a police background check.Uber launched in Calgary last October, despite the City of Calgary not having the regulations in place to allow the company to operate. The city won an injunction against drivers last year, but the two agreed to work together on regulations.Last week, Uber announced it will not operate in Calgary because the city’s rules were too strict. The Uber mobile app is shown on a smartphone in an undated file photo. CITYNEWS
September 28, 2019
Urban Meyer speaks to the media during Ohio State’s football media day Aug. 11.When you hear “Ohio State” or “Michigan,” the rivalry and The Game are one of the first things that come to mind.Growing up in Ohio with OSU alumni in my family, I view The Game no differently. It’s the biggest rivalry in sports with the most intense fans, one that culminates at the end of the football regular season for two teams that want nothing more than to beat each other.Whether you’re a football fan or not, if you hail from Ohio or Michigan, you’re ready to cheer come time for The Game. The most dedicated fans can never waiver to the other side, even for reasons completely unrelated to football.You stick with your team and root for them to win, no matter what.But there are some things even bigger than the biggest rivalry in sports, and one of those things is cancer.When Grant Reed, then 11 years old, now 12 years old, was diagnosed with cancer, he used the rivalry as his motivation to beat the disease, which kept him in the hospital for weeks at a time. Both of Reed’s parents are OSU alumni and former marching band members, so being a Buckeye was something Reed was born into.That’s why Reed decided to name his brain tumor “Michigan.”And then he beat it.Last December, when OSU football coach Urban Meyer found out about Reed’s creative choice in naming his tumor, he visited Reed at Nationwide Children’s Hospital while Reed was still undergoing treatment. Since The Game takes place in Ann Arbor, Mich., this year, Meyer wasn’t able to offer Reed tickets to the game.That’s where Michigan football coach Brady Hoke came in.When Hoke heard about Reed’s tumor, he felt the need to reach out to the young Buckeye fan.“Well I think as a father and a parent, we’re glad in this instance that he beat Michigan, and that’s probably the only time I’ll say it,” Hoke said. “But that’s important, it’s important for us, we’ve got a great, unbelievable opportunity to help kids and help people understand.”He said this was an obvious case where something was more important than the rivalry.“This is a great rivalry, the greatest there is, it’s competitive, and it’s passionate,” Hoke said. “But at the end of the day there’s a heck of lot more things more important than those rivalries.”As I am not a parent, I can’t relate to Hoke’s reasoning for reaching out to Reed in that aspect. But as a human being, you can’t help but feel Hoke’s compassion and the compassion coming from Buckeyes and Wolverines elsewhere.Hoke gave Reed and his family four tickets to come watch the Buckeyes and the Wolverines face off on Nov. 30.Michigan quarterback Devin Gardner agreed that this opportunity wasn’t something the Wolverines and coach Hoke could pass up.“That’s great on the part of coach Hoke. The rivalry is so big, what he’s fighting is so much bigger,” Gardner said. “If what he needs to do is name his deal “Beat Michigan,” I fully support it. But when he comes to The Game, I don’t support that in any way.”
September 24, 2019
Bechtel, the global construction company, has set-up an office in the UAE for its mining and metals business. The office has been set up to service the GCC. Bechtel said that the GCC mining and metals sector has been identified as a major aspect for industrial diversification in the area and this trend is reflected in the scale of awards made during the last 12 months, which reached around $6,000 million. The company is currently constructing one of the world’s largest greenfield aluminium smelter projects – Ras Al Khair – for the Maaden Alcoa joint venture in Saudi Arabia.David Welch, president, Europe, Africa, Middle East at Bechtel, said: “We recognise the growing importance of the Gulf region as a strategic hub for our business. The opening of a regional office for our mining and metals business is a reflection of our ongoing commitment to this region.”He added: “We are optimistic about the business opportunities in the region and we believe the outlook is strong. In addition, the region has excellent connections to European and North African markets. The regional office puts us closer to our customers.”The new regional office will offer services from master planning studies through to engineering execution. Bechtel has completed several hundred major mining and metals projects and more than 1,000 studies across six continents around the world. Projects have included 26 aluminium smelters, 42 major copper projects and 36 major coal projects.
September 21, 2019
Apr 2nd 2017, 7:05 PM By Michelle Hennessy 24,102 Views GARDAÍ HAVE CARRIED out searches at 12 locations today in Dublin, Kildare, and Meath as part of a crackdown on a west Dublin criminal gang.During the operation, the Criminal Assets Bureau seized large amounts of financial documentation, electronic media, a luxury car and a small quantity of controlled drugs and drugs paraphernalia.The searches were conducted at homes and business premises. No arrests were made during the operation today.Gardaí said the investigation is continuing.Read: 14 people found hidden in back of truck at Rosslare port> http://jrnl.ie/3320518 Image: RollingNews.ie Sunday 2 Apr 2017, 7:05 PM Luxury car, drugs and electronics seized in crackdown on west Dublin gang No arrests were made during the operation today. Short URL 10 Comments Share7 Tweet Email Image: RollingNews.ie Tweet thisShare on FacebookEmail this article
September 17, 2019
Recommended for you TCI Premier & Governor gives “all-clear” after Hurricane Irma Related Items:assistance, cabinet, flood, government, help, rain, Tci, water Facebook Twitter Google+LinkedInPinterestWhatsAppCabinet met this week, and among the moves by the Government was to get approved for the renewal of the country’s insurance policy for 2016-2017. Facebook Twitter Google+LinkedInPinterestWhatsApp Happy Hours All Weekend at Outback Steakhouse The CCRIF Caribbean Catastrophic Risk Insurance provides national protection in the event of a tropical cyclone and excess rainfall. The Atlantic Hurricane season is now three days old and lasts until November 30. Hurricane Irma hits TCI
September 17, 2019
Recommended for you Facebook Twitter Google+LinkedInPinterestWhatsAppNASSAU, Bahamas – November 8, 2017 – Information coming out now that former BPL Chairman Leslie Miller was found by the auditors to guide decisions for contract awarding when he was at the helm, in some cases circumventing proper procedure to see an entity win jobs from the country’s power company.Conflicts of interest and curry favoring is cited in the forensic audit report and it exposes that the contracts went to BEC board members and went to public officials; these were the larger contracts and the breech extends back to 2012.Among those getting leading contracts, as they are defined by media reports, one to the brother of current PLP Leader, then Deputy Prime Minister and Minister responsible for BEC, Philip ‘Brave’ Davis. It is said that Davis’ brother did not have the preferred bid for the work, but got the contract despite.Even Mario’s Bowling Alley, owned by Leslie Miller won a contract for over $52,000.Miller’s reply to media was that he was not aware of any contract to Mario’s or to any relative of Davis. Leslie Miller also said that contracts always went to the lowest bidder.Ernst & Young reports that at least 19 vendors circumvented the proper process for awarding of contracts. Related Items:#bplaudit, #bplscandal, #ernst&young, #lesliemiller Bahamas Minister says audit allegation wrong, says Opposition Leader is an ‘honourable man’ Facebook Twitter Google+LinkedInPinterestWhatsApp
September 16, 2019
New downtown Vancouver library offers resources, funThe whole third floor of Vancouver’s new main library is for kids of all ages, beginning with small bright-colored lights in the floor that young children like to follow.If you disembark from the elevator to the left, and turn left again, you’ll soon come to the Early Learning Center, specially designed and equipped for children 5 and younger, and their parents or other caregivers.You’ll find a wealth of play structures where young children can turn things, reach for things, peer through windows and generally play around.“It looks like a bright, beautiful playground, which is exactly the point,” says a library publication.“PLAY is the work of early childhood. The imagination-fueling play the ELC encourages gets children questioning and learning about the world around them, and finding inspiration for their innate curiosity and imagination. While they’re having fun engaging and exploring, they’re also developing pre-literacy skills critical for school readiness.”Even babies are given special images to focus on, and there are nooks for “crawlers” to explore and pull on, the publication says.The center also uses three-dimensional letters and numbers that these very young children learn to recognize — skills that will help prepare them for school and reading.
September 2, 2019
Red, White and Blue host Gary Polland and guest co-host Dr. Laura Murillo discuss the fiscal health of the City of Houston, including the financial implications of this year’s local ballot measures (Proposition A: Rebuild Houston; and Proposition B: Firefighter Pay Parity). With guests Chris B. Brown, Houston City Controller; and Dave Martin, Houston City Council Member and Chairman of the Budget & Fiscal Affairs Committee. Original air date: October 19, 2018.Watch more episodes of Red, White and Blue Share