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first_imgAs red blood cells zip through vessels, they deliver oxygen to nearly every nook and cranny of your body. But oxygen isn’t all they can tote around. By engineering red blood cells to have “sticky” proteins on their surface, a team of researchers has given the cells the ability to carry anything from drugs to treat immune disorders or cancer to radioactive molecules used in imaging of blood vessels.“This is really a great idea, and a very novel approach,” says biochemist Vladimir Muzykantov of the University of Pennsylvania, who was not involved in the new work.Red blood cells account for a quarter of all human cells in the body and survive for an average of 4 months. Their ubiquity and long life makes them an ideal vehicle to carry therapeutics throughout the body, says immunologist Hidde Ploegh of the Massachusetts Institute of Technology in Cambridge. Previously, researchers have loaded red blood cells with drugs by pushing the molecules through the cell’s membrane into its interior, but the process weakens the cell, and the molecules are released only when the cell reaches its final destination.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Ploegh and his colleagues instead wanted to attach molecules to the outside of red blood cells. Because red blood cells don’t have nuclei—and therefore lack genetic material that can be tweaked to make new proteins—the researchers turned to erythroblasts, precursors to red blood cells that still contain DNA. The scientists added to erythroblasts altered versions of genes that are known to encode proteins found on the surface of red blood cells. The introduced gene sequences, though, had modifications so that the erythroblasts produced surface proteins with an extra marker that’s recognized by a protein called sortase.Those engineered proteins remained as the erythroblasts matured into red blood cells. When the researchers added sortase to the matured cell mixtures, the protein snipped off the ends of any proteins the researchers had genetically modified, leaving “sticky” trailer hitches for cargo. Any molecule with a corresponding sortase tag would then bind to the surface protein on the red blood cell. To show that the hitch would work, Ploegh’s team attached the vitamin biotin to red blood cells and infused them into mice. The biotin-toting cells survived for at least 28 days in circulation and did not harm the mice, they report online today in the Proceedings of the National Academy of Sciences.Ploegh envisions the technique being used to create a new type of personalized therapy in the future—your own cells could be isolated, used to create stem cells that differentiate into erythroblasts, genetically modified to carry a molecule, and reinjected into your body. Any molecule that needs to be spread through the circulatory system could be the cargo. By the time the cells have matured back into red blood cells, they will have lost their DNA, eliminating the risk of ongoing mutations or the spread of genetic materials. “The payloads you can install are limitless,” Ploegh says. “But a lot of the applications are still, for now, hypothetical.”Muzykantov, who has developed other approaches for using red blood cells as molecular vehicles, says the significance of the new method “exceeds just drug delivery.” It could be used to track red blood cells to diagnose blood diseases, spread imaging agents throughout the body to visualize atherosclerotic plaques or blocked arteries, or neutralize the immune system before transplants by blocking antibodies that enter the bloodstream.“But there are lots of questions to address in animal models,” he adds. “I would love to see a demonstration that a real drug binds to a red blood cell using this approach and is still effective.”last_img read more

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first_imgThe Congress may have claimed a moral high ground by sacking Maharashtra chief minister Ashok Chavan, but it invited ridicule by meting out a ridiculously lesser punishment to Suresh Kalmadi.The chairman of the Commonwealth Games Organising Committee is linked to scams worth several thousand crores. In the wake of reports of his larger role in the CWG scam, Kalmadi, who is the Congress MP from Pune, had resigned from his post as secretary to the Congress Parliamentary Party (CPP) in August.But his resignation was accepted by party chief Sonia Gandhi just two hours before the winter session of Parliament got underway. The Congress made the announcement about his resignation in an apparent bid to turn the tables against the BJP.”Suresh Kalmadi’s resignation as secretary of the Congress Parliamentary Party has been accepted with immediate effect,” AICC general secretary Janardan Dwivedi said. But the Opposition claims it’s nothing but an eyewash. “Compared to CWG, the Adarsh society scam is peanuts,” an Opposition MP said, adding that the Congress was trying to fool the public by sacking Kalmadi as CPP secretary.BJP spokesperson Prakash Javadekar said Kalmadi’s resignation as CPP secretary meant nothing and that the party would still raise the Games corruption issue in the House. There are five to six CPP secretaries and his removal from this inconsequential post was part of the Congress strategy to deflect public criticism on Games corruption, the BJP said.In fact, not many were even aware that Kalmadi was holding such a post. “People are asking what happens to the scam and loot in the Games, in which there were a group of ministers and secretaries (monitoring the organisation) involved,” the BJP leader said. “We will definitely raise the issue.” Soon after the completion of the Games, the Congress had left Kalmadi to fend for himself, declining to give a clean chit to him or the others associated with the organisation of the Games.advertisementHowever, sources said the party could not sack him from the OC, which is an independent sports body. “He could take the cue from his removal as CPP secretary and quit the OC,” a senior Congress leader said. The Opposition, however, said it would not let Kalmadi to get away easily and raised the CWG scam in the Lok Sabha on Tuesday.Janata Dal (United) leader Sharad Yadav said the scam involved `70,000 crore to `90,000 crore. Kalmadi was not present in the House when the matter was raised.last_img

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first_imgAdvertisement AdvertisementFollowing the departure of Jack Wilshere, Mesut Ozil was given the number 10 jersey as per his request. The former Real Madrid star had worn the No.11 number jersey previously. He waited patiently since 2013 to take over that number from Jack Wilshere who had taken over the No.10 shirt from his former team mate Robin Van persie in the 2012-13 season. After announcing his decision to not renew his contract with his boyhood club earlier this summer, the English midfielder is most likely to make a move to the Turkish league with interests coming from Crystal palace and West Ham as well.Mesut Ozil, on the other hand was extremely delighted to claim the No.10 shirt from him. He took to social media to express his delight. Arsenal signed the German play-maker from Real Madrid in 2013 for €47m. He had been wearing the No.11 shirt since then. Upon claiming his new shirt, he said that It was more than just a number and it means a lot to him wearing it next season.🔟 – It’s more than just a number. Means a lot to me wearing it next season! Thanks, @arsenal 🙏🏼〽 #YaGunnersYa #M1Ö pic.twitter.com/M7ZTtMdirb— Mesut Özil (@MesutOzil1088) July 3, 2018Along the years, the No.10 shirt have been worn by some Arsenal greats. To name a couple, Legendary Dutch forwards Dennis Bergkamp and Robin Van persie have both donned the jersey. Mesut Ozil is expected to join the arsenal camp earlier than scheduled before following Germany’s shock elimination from the group stages of the FIFA World Cup 2018 in Russia. Ozil now wears No. 10 shirt for both club and country.Read also :Football: Riyad Mahrez set to join Manchester City this week as Leicester City accepts a £60m bidFootball: Samurai Blue and their fans receive worldwide praise for leaving with dignity after defeatlast_img read more

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first_imgSouth Africa have been boosted by the return of fit-again Chris Morris for the first Test against India starting January 5 at Newlands in Cape Town.South Africa have also included captain Faf du Plessis and pacer Dale Steyn in the 15-man squad after both missed the historic four-day day-night Test against Zimbabwe earlier this week. Both Du Plessis and Steyn were laid low by flu this week.Pace bowler Chris Morris has been restored to South Africa’s squad after recovering from a groin injury. Morris replaces Duanne Olivier in the squad for the Test, which starts next Friday.There is also a return for Quinton de Kock, who hurt his hamstring in the Boxing Day Test and was unable to keep wicket in Zimbabwe’s two innings.The Proteas will assemble in Cape Town on January 2 to begin preparations for the first Test of the three-match series.South Africa won by an innings and 120 runs inside two days at St George’s Park in Port Elizabeth and now meet India over three Tests in January.Squad: Faf du Plessis (captain), Hashim Amla, Temba Bavuma, Quinton de Kock, Theunis de Bruyn, AB de Villiers, Dean Elgar, Keshav Maharaj, Aiden Markram, Morne Morkel, Chris Morris, Andile Phehlukwayo, Vernon Philander, Kagiso Rabada, Dale Steyn.(With inputs from Reuters)ALSO WATCHlast_img read more

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first_imgManchester United new boys Aaron Wan-Bissaka and Daniel James have proved that sometimes footballers should stick to their skill set on the pitch.During their initiation to their Red Devils teammates during a dinner on the Australian pre-season tour, both players were required to get up on stage and belt out a song.But Man Utd fans will be hoping their on-field performances are better than their singing voices, after their acts sent teammates into hysterics. Editors’ Picks ‘Everyone legged it on to the pitch!’ – How Foden went from Man City superfan to future superstar Emery out of jail – for now – as brilliant Pepe papers over Arsenal’s cracks What is Manchester United’s ownership situation and how would Kevin Glazer’s sale of shares affect the club? Ox-rated! Dream night in Genk for Liverpool ace after injury nightmare Wan-Bissaka, who joined from Crystal Palace for £50 million ($63m), struggled to get into rhythm with his version of rapper Nav’s ‘Tap’, as he spoke the words while reading them off a mobile phone.🎤 Angel Gomes’ Instagram Story: Aaron Wan-Bissaka sings his initiation song (IG: angel.gomes10) #manutd #mufc🎶 Tap by NAV (ft. Meek Mill) pic.twitter.com/fVYJCmJBEL— RedCafe.net (@red_cafe) July 10, 2019James didn’t fare much better as the £15m ($19m) signing from Swansea also left the Red Devils players amused after an attempt at singing Uncle Kracker’s ‘Follow Me’.🎤 Angel Gomes’ Instagram Story: Daniel James sings his initiation song (IG: angel.gomes10) #manutd #mufc🎶 Follow Me by Uncle Kracker pic.twitter.com/xyT6QtOhb2— RedCafe.net (@red_cafe) July 10, 2019The duo were eventually upstaged by an incredible performance from Scottish midfielder Scott McTominay, who crooned out an outstanding effort at ‘Ain’t No Sunshine’ by Bill Withers that sent the crowd wild.🎤 Aaron Wan-Bissaka’s Instagram Story: Scott McTominay sings (IG: a_bissaka) #manutd #mufc🎶 Ain’t No Sunshine by Bill Withers pic.twitter.com/9ffnUvU3OW— RedCafe.net (@red_cafe) July 10, 2019Manchester United are currently in Australian city Perth as they prepare for their first friendly match of the pre-season against A-League premiers Perth Glory.The tour has so been overshadowed by speculation surrounding the futures of stars Paul Pogba and Romelu Lukaku, with coach Ole Gunnar Solskjaer insisting that no bids have been received for the duo and they are not for sale.The Norwegian also denied there was a spat between Pogba and Jesse Lingard, suggesting there was a media agenda against the French World Cup winner.Following the Glory match, United will take on old rivals Leeds United in Perth on July 17 before journeying north to south-east Asia to continue their tour.They will then meet Inter in Singapore on July 20 and Tottenham in Shanghai five days later as part of the International Champions Cup.United’s Premier League campaign begins at Old Trafford against Frank Lampard’s Chelsea on August 11.last_img read more

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first_imgSouthampton: India captain Virat Kohli “is doing fine” despite being hit on his thumb while batting in the nets ahead of the team’s World Cup opener against South Africa here on Wednesday. “He got hit while batting but is doing fine. There is nothing to worry as of now,” team sources told PTI. Kohli hurt his thumb during a training session at the Ageas Bowl here on Saturday and physiotherapist Patrick Farhat to attend to the Indian skipper. Also Read – We don’t ask for kind of tracks we get: Bowling coach Arun Farhat was first seen using magic spray on the injured finger and then applied tape on it. Later Kohli was seen leaving the field with his thumb dipped in a glass of ice. India, one of the favourites for the title, were hit by injuries in the run up to the World Cup. While all-rounder Vijay Shankar had to sit out of the warm-up game against New Zealand after hurting his elbow, Kedar Jadhav is still recovering from a shoulder injury he picked up during IPL and missed India’s both warm-up games against the Kiwis and Bangladesh. Jadhav, a key figure in India’s middle-order, batted in the nets on Saturday, an indication that he could be fit in time for the game against South Africa. The Indian team has an off day on Sunday.last_img read more

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first_imgTORONTO – The Ontario government is increasing access to transition-related surgeries in the province.Health Minister Eric Hoskins says the province will offer genital transition surgery for the first time next year.He says that will make Ontario only the second jurisdiction in Canada to provide access to such surgery.Hoskins also says the province will be working with the Toronto-based Women’s College Hospital to increase access to “top” or chest surgery.The developments come after the province expanded access last year to referrals for transition-related surgeries, although patients often had to travel out of the province for procedures.Previously, only the Gender Identity Clinic at the Centre for Addiction and Mental Health in Toronto could refer a patient for sex reassignment surgery, which is covered by the Ontario Health Insurance Plan, but last year’s referral change meant qualified health-care providers anywhere in Ontario could refer transgender patients for surgery.last_img read more

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first_imgThe Canadian Press PENTICTON, B.C. — Residents of British Columbia’s southern Okanagan will gather this evening for a candlelight vigil to honour four people shot to death in a targeted attack in Penticton.The vigil is set to begin at 6:30 p.m. in Gyro Park, just a few blocks from a duplex where 71-year-old Rudi Winter died Monday in the first of two shootings.Police say another man and two women, all in their 60s and 70s, were fatally shot in neighbouring homes in a separate area of the city less than an hour later.RCMP Supt. Ted De Jager says 68-year-old John Brittain then walked into the Penticton RCMP detachment and surrendered.The former employee in the city’s engineering department is charged with three counts of first-degree murder and one count of second-degree murder and remains in custody awaiting his next court date on May 8.Longtime Penticton resident Sigrid Boersma says Monday’s shootings have left her feeling “shaky” and “insecure” while former mayor and current member of the legislative assembly Dan Ashton says the incidents have been “very traumatic.”last_img read more

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Rabat – Regional road 408 will be extended by 38 kilometres between Taounate and Ouazzane in northern Morocco.The province’s governor, Hassan Belhadfa, launched the 18-month, MAD 80 million project on Thursday, June 1.The Road Fund (CFR) will finance the project under the Ministry of Equipment, Transport, Logistics and Water. The reinforcement of the road between 136 and 174 kilometres will enhance the accessibility of the road network, improving the living conditions of people living in isolated areas.The new roadwork will create access to three communes in the Taounate province: Mezroua, Jbabra and Ouertzagh.The whole road network across the province will be upgraded by 2022, by which time over MAD 1.06 billion will have been invested into the project. The total length of the roads in the Taounate province is 1,240 kilometres. read more

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The Council, in two resolutions adopted on 17 June, split the sanctions it has imposed on Al-Qaida and those against the Taliban, creating two lists of individuals and organizations so that they can be treated separately.Sanctions originally created for the Taliban were converted into a global Al Qaida terrorist listing regime, while the Taliban will be covered by resolution 1988 which is based on a territorial limitation and the identification of the situation in Afghanistan as constituting a threat to international peace and security.In a statement issued in Geneva, Martin Scheinin, the UN Special Rapporteur on human rights and counter-terrorism, said “the Al Qaida sanctions regime under resolution 1989 does not, judged by the letter of the resolution, remedy the human rights shortcomings expressed in relation to the earlier consolidated list.”Judicial challenges to the listings are likely to continue, he said.“Due to the unsatisfactory level of due process guarantees such as disclosure of information and a right to an effective remedy, the strengthened role of the ombudsperson is unlikely to satisfy national or European courts that the safeguards at the United Nations level are sufficient, so that these courts could allow deference instead of exercising their jurisdiction over the national or European measures for the implementation of the sanctions,” said Mr. Scheinin.However, he added that his assessment may change if Security Council members are prepared to secure the following conditions:Any listing proposal require the submission of the full set of information that is used as the substantive basis for the listing proposal;The person or entity subjected to the listing proposal has the right and practical means to effectively challenge the proposal;The delisting ombudsperson has access to the full set of information used for the listing;The delisting recommendations by the ombudsperson or delisting proposals by the designating State are in practice respected.“If these conditions are met in the implementation… the Special Rapporteur finds it likely that national or European courts will require listed individuals or entities to exhaust the delisting procedure of the ombudsperson before exercising their jurisdiction in relation to the national or European implementing measures,” said Mr. Scheinin. 29 June 2011An independent United Nations human rights expert today said that the new procedure adopted by the Security Council on the listing of individuals and organizations under the international sanctions regime against terrorism still fails to address the human rights shortcomings in the process. read more

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The Toronto stock market was listless Thursday amid concerns about the role of central banks in supporting the economic recovery and a forecast of lower than expected growth by the World Bank.The S&P/TSX composite index inched up 1.31 points to 12,111.2, off early lows as miners, financials and tech stocks all turned positive. The Canadian dollar was ahead 0.48 of a cent to 98.4 cents US amid lower commodity prices.U.S. indexes were also little changed amid positive readings on retail sales and claims for jobless benefits as the Dow Jones industrials shed 1.92 points to 14,993.31. The Nasdaq declined 4.18 points to 3,396.25 while the S&P 500 index was up 0.59 of a point to 1,613.09.The U.S. Commerce Department said that retail sales increased 0.6 per cent in May from April. That’s up from a 0.1 per cent gain the previous month and the fastest pace since February. The gain shows consumers remain resilient despite higher taxes and could drive faster growth later this year. The April gain was led by a 1.8 per cent jump in auto sales, the biggest increase in six months.The number of Americans seeking unemployment benefits dropped 12,000 to a seasonally adjusted 334,000 last week. The four-week average, a less volatile measure, decreased 7,250 to 345,250. Applications are a proxy for layoffsCentral bank worries had also pushed Toronto and New York markets lower Wednesday as the TSX fell 114 points — its eighth loss in nine sessions — and the Dow fell 127 points.Worries about central banks have been growing ever since Federal Reserve chief Ben Bernanke said on May 22 that the Fed might pull back on its US$85 billion-a-month bond-buying program, known as quantitative easing, if economic data improves, especially hiring. The QE program has fuelled a strong rally on U.S. markets.Now Japanese media reports are saying overseas hedge funds may be dumping the country’s equities following disappointment over the Bank of Japan’s decision earlier in the week to refrain from additional monetary easing measures.Those reports helped send Tokyo’s Nikkei 225 index plunging 6.4 per cent, while the yen strengthened 1.5 per cent against the greenback. A rising yen spells bad news for Japanese manufacturers because it will make their exports look more expensive overseas.In April, the Bank of Japan announced a massive stimulus in an attempt to get inflation up to two per cent. The euphoria that drove the Nikkei up to five-year highs followed by wild fluctuations. The index is now around 20 per cent down from its May 23 peak, leaving the market in bear market territory.Commodity prices were lower as the World Bank lowered its global economic-growth forecast, saying it expects expansion of only 2.2 per cent this year, down from a 2.4 per cent projection issued in January.In its semiannual Global Economic Prospects report, the World Bank also revised lower its expectations for growth in China, Brazil and India. At the same time, it upped growth estimates for Japan and the U.S.The gold sector led TSX decliners, down 0.55 per cent as August bullion on the Nymex fell $6.80 to US$1,385.20 an ounce. Barrick Gold Corp. (TSX:ABX) faded 23 cents to C$19.96.The industrials sector declined 0.45 per cent and Canadian Pacific Railway (TSX:CP) was down $1.03 to $124.42.The energy sector was off 0.2 per cent while the July crude contract on the New York Mercantile Exchange moved down 19 cents to US$95.69 a barrel. But Imperial Oil (TSX:IMO) ran ahead 58 cents to $39.47.Speculation that the Fed will begin to wind down its quantitative easing program has also had the effect of pushing U.S. Treasury yields sharply higher, which in turn has had a negative effect on TSX defensive sectors such as real estate, utilities, telecoms and pipelines.The utilities component was lower Thursday as Just Energy Group (TSX:JE) fell 14 cents to $6.28.The base metals sector gained 1.7 per cent as July copper lost two cents to US$3.20. Teck Resources (TSX:TCK.B) was up 53 cents to $24.59.Financials gained 0.35 per cent while Royal Bank (TSX:RY) climbed 25 cents to $59.28.The tech sector was also supportive as BlackBerry (TSX:BB) improved by 70 cents to $14.57.Earnings news and acquisitions also provided lift for the TSX.Empire Company Ltd. (TSX:EMP.A) and its wholly-owned subsidiary, Sobeys Inc. announced Wednesday after the close that they are buying rival Canada Safeway Limited for $5.8 billion in cash. Empire shares jumped $7.44 or 11 per cent to $75.05.Shares in Transat A.T. Inc. (TSX:TRZ.B) ran up 53 cents or 10 per cent to $5.84 as the travel company posted a net loss of $22.8 million or 59 cents per share in the quarter ended April 30. On an adjusted after-tax basis, Transat lost $1.43 million or four cents per share, which was far better than the 26 cents per share loss estimated by analysts and an improvement from a loss of 64 cents per share in the second quarter of 2012.Elsewhere in Asia, the Hang Seng index fell 2.2 per cent while the Kospi in South Korea lost 1.4 per cent.Mainland Chinese were pummelled as accumulating signs of a slowdown in growth in the world’s number-two economy caused investors to retreat. The Shanghai Composite Index slid 2.8 per cent to its lowest close in six months.European bourses were mixed with London’s FTSE 100 index down 0.06 per cent, Frankfurt’s DAX fell 0.58 per cent and the Paris CAC 40 dropped 0.15 per cent. read more

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Uber has rolled out an in-app option for riders to tip their driver in five Canadian cities and plans to implement the feature across Canada and the U.S at the end of July. The new feature, which went into effect Thursday, is available in a total 121 cities in Canada and the U.S. The tipping feature is currently available in Toronto, Calgary, Edmonton, Windsor, Ont. and Kingston, Ont. Uber says the feature was implemented after requests from drivers and riders for the option to tip on the app, rather than in cash. Drivers were only recently allowed to ask for cash tips following the settlement of a US$100 million class-action lawsuit in 2016, which further clarified the status of their drivers as independant contractors, rather than employees. Uber drivers will not be able to see how much you tip them until they give you a passenger rating.The Canadian Press read more

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Sumanthiran said that there were some reservations by some minority parties during the process to draft a new Constitution on abolishing the Executive Presidency.However he said that following the recent incidents in the country it was clear there is a need to abolish the Executive Presidency. The Tamil National Alliance (TNA) and the Sri Lanka Muslim Congress (SLMC) are to support to the 20th Amendment to Constitution.The position of the TNA and SLMC was conveyed to Parliament during a debate today on abolishing the Executive Presidency TNA MP, M.A. Sumanthiran said that after the 2015 Presidential elections, Tamils assumed that the Executive Presidency, as a system of Government will be abolished soon. However he noted this was done only in part through the 19th Amendment and there was an expectation that the rest will be done through a new Constitution. SLMC leader Rauff Hakeem said that successive Presidents promised to abolish the Executive Presidency but instead they attempted to abuse its powers.However he said abolishing the Executive Presidency cannot be done without a Referendum.  (Colombo Gazette) read more

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Brock alumna Jenine Dilts-Bayman (BSM ’04) is one of 10 finalists in the AusMumpreneur Awards ‘Making a Difference’ category.Brock alumna Jenine Dilts-Bayman (BSM ’04) is a long way from campus, but she’s looking for some local help in an Australian contest that recognizes entrepreneurial mothers.She is one of 10 finalists in the AusMumpreneur Awards ‘Making a Difference’ category.In 2012, Dilts-Baymen founded Mums with Bubs Fitness, which helps women maintain and regain their health and fitness through the challenges of motherhood.Deadline for voting is Oct. 6 at 10 a.m. EST. The winner will be announced Oct. 11 in Melbourne. read more

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first_imgOutotec and Hatch, an unincorporated Joint Venture, have been awarded a contract by the Ma’aden and Alcoa JV to provide an integrated digestion and evaporation facility to what will reportedly be the lowest cost aluminium complex in the world – the Ma’aden project in Ras Az Zawr, Saudi Arabia. The Outotec-Hatch overall contract value is approximately EUR50 million, with roughly equal share of the work between the two. The delivery of the facility includes a technology license, detailed engineering, procurement support and construction support services. Outotec and Hatch have jointly developed and own the tube digestion and integrated evaporation technologies to be installed at this alumina refinery. It will have an initial annual capacity of 1.8 Mt alumina, with first production expected in 2014.The Ma’aden aluminium project comprises a fully integrated greenfield complex with bauxite mine, alumina refinery, aluminium smelter and can sheet rolling mill. It will contribute to the development of a world-class aluminium industry in the Kingdom of Saudi Arabia and is designed with the potential for future expansion. The Al Baítha site consists of a bauxite mine and ore handling facilities and is located near Quiba in northeast Saudi Arabia.The mine plan has been prepared based upon current estimated capacities of the refinery and smelter reviewed in completed technical studies and envisages production at an annual mining rate of 4 Mt/y of bauxite for a period in excess of 30 years.The Ras Az Zawr site comprises a plot of land 90 km north of Jubail on the coast of the Arabian gulf. A segment of the site is proposed to be used for the construction of the alumina refinery, aluminium smelter, rolling mill and related infrastructure for the Aluminium Complex. Bauxite ore transported by rail to Ras Az Zawr will be refined to produce alumina, which will in turn be processed in the smelter on site to produce 740,000 t/y of aluminium.The rolling mill with initial hot-mill capacity of between 250,000 and 460,000 t/y will focus initially on the production of sheet, end and tab stock for the manufacture of cans and other products. Aluminium operations at Ras Az Zawr will rely on certain infrastructure with a key item being a power, steam and water facility. In October 2009 Ma’aden signed an agreement with the Saline Water Conversion Co (SWCC) and Saudi Electricity Company (SEC) to develop a joint power and desalination plant which will generate 2,400 MW of electricity and 1.025 million m3/d of water. Of that, the aluminium complex will use 1,350 MW of electricity and 25,000 m3/d of water. The rest of the water will be pumped to the cities of Riyadh, Hafr Al-Batin and Nuayriyah. SEC’s share will be 1,050 MW of electricity, some of which will power downstream industries at the Mineral Industry Complex at Ras Az Zawr.“We are delighted that Ma’aden Aluminium Project chose the unique Outotec-Hatch alumina digestion and evaporation technology  for this facility which will be one of the most technologically advanced aluminium complex in the world and utilise low-cost and clean power generation. As our core business is the development of sustainable solutions for our planet, we are very proud to be involved in this project”, says Outotec CEO Pertti Korhonen.last_img read more

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first_imgClick to enlarge Disgruntled DOL customers rejoice: Vancouver driver licensing offices are experiencing some of the lowest wait times in years. The Washington Department of Licensing attributes statewide wait time reductions to expanded online and mail-in options, and to moving driver testing to qualified driver training schools.The average wait time in the first half of January for the Vancouver North office on Northeast 117th Avenue was six minutes, while the Vancouver East location on Northeast 136th Avenue averaged eight minutes.Last year, the DOL added the option to pre-apply online for a driver’s license and introduced an application called License Express that allows drivers to take care of the most common transactions for all of their vehicles and licenses in one spot.In 2012, nearly one-quarter of the agency’s 3.4 million driver transactions were done by mail or online, according to a news release from the DOL. Over the last five years, that percentage has grown from 5 percent to 23 percent.However, local service innovations came with a caveat. Vancouver licensing office customers experienced longer than average wait times this summer while employees were learning to use upgraded counter equipment. In July, the average wait time spiked to 79 minutes at Vancouver East and 73 minutes at Vancouver North; that’s more than five times the average of the previous summer.last_img read more

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first_imgNizamabad: Light rains have been recorded in Nizamabad and Kamareddy districts for the past two days, making the atmosphere cool. Since the last two days, i.e., Sunday and Monday, were holidays due to Bonalu festival, people remained indoors.According to a report released by Telangana State Development Planning Society here on Monday, 44.5 mm of rain was recorded in Patharajampet in Kamareddy district. 44 mm in Gandhari, 42.3 mm in Machareddy, 41.3 mm in Lachchapet, 33.8 mm in Ramareddy, 33.8 mm in Tadvai, 33.8 mm in Sadashivpet, 30.8 mm in Bibipet, 30.8 mm in Domakonda and 30.5 mm rain was recorded in Sarwarpur. Lake Pandu Bodhan was filled with rain water for the last two days Also Read – Hyderabad: Intermediate student dies of cardiac arrest in class Advertise With Us TSDPS Assistant Executive Officer B Venumadhav said Maggidi village, Armoor mandal, Nizamabad district, had received the highest rainfall of 54.5 mm. Meanwhile, 39.8 mm rainfall recorded in Veilpur, 38.3 mm in Khammerpalli and Konasamudram, 37.5 mm in Nandipeta Tandur, 36.7 mm in Macherla (Armoor mandal), 35 mm in Bingal and Chandur, 33.8 mm in Sirikonda Thummanapalli and 33.8 mm in Maklur, he said. Also Read – Vemulawada school seized after road accident Advertise With Us Agriculture Officer Mekala Govind said that these rains are useful for crops in the district. Meanwhile, another depression will be formed in Bay of Bengal in the end of July month. Its impact is expected to last for a few more days. Depression in the northwest Bay of Bengal crossed West Bengal and Jharkhand coast on Sunday morning. On the other hand, the surface rotation, which occurred here, is tilted to the southwest at an elevation of 7.6 km above sea level. As a result of this, by July 31, there will be low pressure. Nizamabad and Kamareddy districts are likely to receive mild to moderate rains and heavy rains on Tuesday. The Indian Meteorological Department (IMD) has said that there will be light rains or showers over the next three days.last_img read more

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first_imgListen To embed this piece of audio in your site, please use this code: Marissa CummingsCody Francisco (Certified Deaf Interpreter) displaying his strategy for success.Houston is one of the most diverse cities in the U.S. so it’s fitting for it to have hosted the Fifth Annual International Language Services Conference on Friday. Over 90 different languages are spoken within Houston.  The conference brought together translators and interpreters to work on providing the most effective communication services in health care.Cody Francisco is a Certified Deaf Interpreter (CDI) and medical interpreter. He is deaf himself and provides a cultural understanding in his translating. “So my job as a CDI is to provide that cultural information and become bilingual and bicultural, so I can provide both of those, which is required for me as an interpreter,” said Francisco, translated by an interpreter.The conference was sponsored by MasterWord, a language service provider company.Mila Golovine, the president of MasterWord, wants people to know the importance of using a professional interpreter versus friends or family.“The difference between speaking a foreign language and being able to interpret can be compared to the difference of knowing how to drive a car and knowing how to repair your car,” said Golovine.Every year thousands of international patients come to the Texas Medical Center increasing the need for language providers. X 00:00 /00:59 Sharelast_img read more